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This leaflet is for small and medium-sized companies in the chemical manufacturing industry, although the principles also apply to larger businesses.
It identifies the main hazards of carrying out chemical reactions, provides guidance on how you can ensure a safe operation, and identifies some sources of further information and advice.
This guidance has been reviewed in 2014. The advice it contains is unchanged but references have been updated.
Article source: http://www.hse.gov.uk/pubns/indg254.htm